Transcription is mechanism by which the base sequence of the section of DNA, representing a gene is converted into the complementary base sequence of mRNA.
DNA is found in the nucleus and gives instructions to cells on what type of protein to be produce. The formation of proteins requires the linking together amino acid in a correct sequence by peptide bond information about these sequence is contain in the DNA which is carried the ribosome by the synthesized mRNA
These usually begins with the unzipping of the DNA, the unzipping is facilitated by the fact the bases are held together by weak hydrogen bond. The unzipping is done by the enzyme called helicase, free nucleotides aline themselves using one of the DNA strand as a template, for the formation of the complementary single strand of mRNA, this is done with the influence of the enzyme called RNA polymerase. During these process, the enzyme moves along the 5 prime to 3 prime direction, the mRNA is then pulled off from the nucleus and goes out through the nuclear pore to the cytoplasm where it confines the message to ribosome which is then used for protein synthesizes. RNA polymerase molecule then leaves the DNA, the unzipped region of the DNA then zips back.
Genetic information is copied from DNA by mRNA and the sequence of bases in mRNA determines the sequence of amino acid in a given protein molecule to be formed
A group of 3 bases or triplet of bases forms a cordon and each cordon codes for a specific amino acid. There are four bases in a DNA molecule and 20 common amino acid which must be coded for by four bases.
If one base was to code for one amino acid, then only four amino acid will be coded for and if two base were to code for one amino acid then only 16 amino acid will be coded for, but the 4 bases can convinently code for the 20 different amino acid that is 43=64 cordons (xg) where x=total number of bases and y= the number of bases use in each cordons.
64 cordons can conviently code for the 20 different amino acid. Each amino acid is carried by tRNA and tRNA has a lope containing a triplet of bases called anti-cordons which is complementary to each cordon of mRNA.