Mesopotamia civilization, unlike that of Ancient Egypt was created along two rivers (and not one river). Secondly, many people were involved in this civilization (unlike one people in the case of Ancient Egypt). Thirdly, much warfare and conflict marked Mesopotamia's civilization. Fourthly, the structures erected in Mesopotamia were built of mostly clay while those in Ancient Egypt were made of stones or rocks as the main components. The Mesopotamia civilization was created by groups such as the Sumerians, the Babylonians, the
Assyrians, the Chaldeans and the Persians.
Note: the Chaldeans were also called the second Babylonian empire, they seized Nineveh with the assistance of Medes, ending the Assyrian empire. The made Nineveh the most beautiful city of Babylon. They were led by Nebuchadnezzar during this period.